eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| perineural cyst | ||||
| Disease ID | 1061 |
|---|---|
| Disease | perineural cyst |
| Definition | Perineurial cysts commonly found in the SACRAL REGION. They arise from the PERINEURIUM membrane within the SPINAL NERVE ROOTS. The distinctive feature of the cysts is the presence of spinal nerve root fibers within the cyst wall, or the cyst cavity itself. |
| Synonym | cyst nerve root cyst of nerve root cyst of the nerve root cyst tarlov cyst tarlovs cyst, perineural cyst, perineurial cyst, sacral perineural cysts nerve root cysts perineural cysts perineurial cysts tarlov cysts tarlov's cysts, perineural cysts, perineurial cysts, sacral perineural cysts, sacral tarlov cysts, tarlov nerve root cyst perineural cysts perineurial cyst perineurial cyst (disorder) perineurial cysts root nerve cyst sacral perineural cyst sacral perineural cysts sacral tarlov cysts tarlov cyst tarlov cysts tarlov cysts [disease/finding] tarlov's cyst |
| Orphanet | |
| UMLS | C0520720 |
| MeSH | |
| SNOMED-CT | |
| Comorbidity | UMLS | Disease | Sentences' Count(Total Sentences:3) C0700594 | radiculopathy | 2 C0524812 | intracranial hypotension | 2 C0392548 | cauda equina syndrome | 1 |
| Curated Gene | (Waiting for update.) |
| Inferring Gene | (Waiting for update.) |
| Text Mined Gene | (Waiting for update.) |
| Locus | (Waiting for update.) |
| Disease ID | 1061 |
|---|---|
| Disease | perineural cyst |
| Integrated Phenotype | HPO | Name(Total Integrated Phenotypes:15) HP:0000802 | Impotence HP:0003401 | Paresthesia HP:0000925 | Abnormality of the vertebral column HP:0005107 | Abnormality of the sacrum HP:0004375 | Neoplasm of the nervous system HP:0000763 | Sensory neuropathy HP:0002607 | Bowel incontinence HP:0001324 | Muscle weakness HP:0002839 | Urinary bladder sphincter dysfunction HP:0001284 | Areflexia HP:0002027 | Abdominal pain HP:0001482 | Subcutaneous nodule HP:0010830 | Impaired tactile sensation HP:0002797 | Osteolysis HP:0002315 | Headache |
| Text Mined Phenotype | HPO | Name | Sentences' Count(Total Phenotypes:6) HP:0003418 | Back pain | 2 HP:0002615 | Low blood pressure | 2 HP:0012641 | Decreased intracranial pressure | 2 HP:0012531 | Pain | 1 HP:0002835 | Aspiration | 1 HP:0003419 | Low back pain | 1 |
| Disease ID | 1061 |
|---|---|
| Disease | perineural cyst |
| Manually Symptom | UMLS | Name(Total Manually Symptoms:1) C0458224 | piriformis syndrome |
| Text Mined Symptom | UMLS | Name | Sentences' Count(Total Symptoms:1) |
Manually Genotype(Total Text Mining Genotypes:0) |
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| (Waiting for update.) |
Text Mining Genotype(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
All Snps(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
GWASdb Annotation(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
GWASdb Snp Trait(Total Genotypes:0) | |
|---|---|
| (Waiting for update.) | |
Mapped by lexical matching(Total Items:5) | ||||
|---|---|---|---|---|
| HP ID | HP Name | MP ID | MP Name | Annotation |
| HP:0000925 | Abnormality of the vertebral column | MP:0009005 | abnormal sesamoid bone of gastrocnemius morphology | any structural anomaly of the small sesamoid bones situated behind the condyles of the femur |
| HP:0001324 | Muscle weakness | MP:0000746 | weakness | state of being infirm or less strong than normal |
| HP:0005107 | Abnormality of the sacrum | MP:0020010 | decreased bone mineral density of femur | reduction in the quatitative measurment value of mineral content of bone in the long bone of the thigh |
| HP:0002839 | Urinary bladder sphincter dysfunction | MP:0011874 | enlarged urinary bladder | increased size of the distensible musculomembranous organ that serves to collect and store urine excreted by the kidneys |
| HP:0004375 | Neoplasm of the nervous system | MP:0010287 | increased reproductive system tumor incidence | greater than the expected number of tumors originating in the reproductive system in a given population in a given time period |
Mapped by homologous gene(Total Items:14) | ||||
|---|---|---|---|---|
| HP ID | HP Name | MP ID | MP Name | Annotation |
| HP:0002797 | Osteolysis | MP:0020137 | decreased bone mineralization | decrease in the rate at which minerals are deposited into bone |
| HP:0004375 | Neoplasm of the nervous system | MP:0014171 | increased fatty acid oxidation | increased rate or incidence of the process of removal of one or more electrons from a fatty acid, with or without the concomitant removal of a proton or protons, by reaction with an electron-accepting substance, by addition of oxygen or by removal of hydr |
| HP:0002315 | Headache | MP:0020137 | decreased bone mineralization | decrease in the rate at which minerals are deposited into bone |
| HP:0000802 | Impotence | MP:0012504 | increased forebrain apoptosis | increase in the number of cells of the forebrain undergoing programmed cell death |
| HP:0005107 | Abnormality of the sacrum | MP:0020010 | decreased bone mineral density of femur | reduction in the quatitative measurment value of mineral content of bone in the long bone of the thigh |
| HP:0000763 | Sensory neuropathy | MP:0014185 | cerebellum atrophy | acquired diminution of the size of the cerebellum associated with wasting as from death and reabsorption of cells, diminished cellular proliferation, decreased cellular volume, pressure, ischemia, malnutrition, reduced function or malfunction, or hormonal |
| HP:0001284 | Areflexia | MP:0020220 | decreased tear production | decreased production of the amount of fluid produced in the eye |
| HP:0002027 | Abdominal pain | MP:0020220 | decreased tear production | decreased production of the amount of fluid produced in the eye |
| HP:0003401 | Paresthesia | MP:0014185 | cerebellum atrophy | acquired diminution of the size of the cerebellum associated with wasting as from death and reabsorption of cells, diminished cellular proliferation, decreased cellular volume, pressure, ischemia, malnutrition, reduced function or malfunction, or hormonal |
| HP:0001482 | Subcutaneous nodule | MP:0013542 | abnormal submandibular gland branching morphogenesis | |
| HP:0002839 | Urinary bladder sphincter dysfunction | MP:0012676 | dilated brain ventricles | the luminal space of one or more of the four communicating cavities within the brain that are continuous with the central canal of the spinal cord is increased in volume or area, usually with an increase in contained fluid |
| HP:0001324 | Muscle weakness | MP:0020309 | increased creatine kinase activity | increased ability of to catalyze the reaction: ATP + creatine = N-phosphocreatine + ADP + 2 H(+). |
| HP:0002607 | Bowel incontinence | MP:0013438 | dysmyelination | reduced amount of myelin present in the form of a myelin sheath surrounding an axon due to defects in the synthesis and formation of myelin |
| HP:0000925 | Abnormality of the vertebral column | MP:0020137 | decreased bone mineralization | decrease in the rate at which minerals are deposited into bone |
| Disease ID | 1061 |
|---|---|
| Disease | perineural cyst |
| Case | (Waiting for update.) |